Know the signs

Early signs

Recognition of the early symptoms of SJS/TEN, accurate diagnosis and prompt medical attention are the most invaluable tools in minimising the possible long-term effects.

Initial symptoms may be non-specific in nature and may include:

  • Fever
  • Malaise
  • Flu-like symptoms


Further symptoms may follow and may involve:

  • Mucous membranes – blisters to the mouth, eyes, ears, nose, genital area
  • Swelling of eyelids and itchy, red eyes
  • Blistering rash to variable percentage of the body

If it is suspected that the reaction is due to a drug, the symptoms can take one or two weeks to manifest from the first time the patient takes the drug. Always contact your doctor before deciding to stop a drug.