Know the signs

Early signs

Recognition of the early symptoms of SJS/TEN, accurate diagnosis and prompt medical attention are the most invaluable tools in minimising the possible long-term effects.

Initial symptoms may be non-specific in nature and may include:

  • Fever
  • Malaise
  • Flu-like symptoms


What can cause SJS/TENS?

Although all medications including over-the-counter and herbal medicines have the potential to cause SJS/TEN, the most commonly implicated are:

  • Anti-convulsants (drugs used for epilepsy), for example:
    • Carbamazepine
    • Lamotrigine
    • Phenytoin
  • Antibiotics, for example:
    • Penicillin
    • Cephalosporin
    • Sulphonamides
  • Non-Steroidal Anti-inflammatory medications (NSAIDs), for example:
    • Ibuprofen
  • Anti-gout medications, for example
    • Allopurinol

Other Causes include Viral, Bacterial and Fungal Infections.